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sigM ECF RNA polymerase sigma factor SigM [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886246, updated on 6-Oct-2023
Gene symbol
sigM
Gene description
ECF RNA polymerase sigma factor SigM
Locus tag
Rv3911
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (4400186..4400854)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene mutator protein MutT Neighboring gene hypothetical protein Neighboring gene peptidoglycan biosynthesis protein Neighboring gene anti-sigma-M factor RsmA Neighboring gene thioredoxin reductase Neighboring gene thioredoxin TrxC

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Mycobacterium tuberculosis SigM positively regulates Esx secreted protein and nonribosomal peptide synthetase genes and down regulates virulence-associated surface lipid synthesis. Raman S, et al. J Bacteriol, 2006 Dec. PMID 17028284, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These findings demonstrate that SigM positively and negatively regulates cell surface and secreted molecules that are likely to function in host-pathogen interactions.
    Title: Mycobacterium tuberculosis SigM positively regulates Esx secreted protein and nonribosomal peptide synthetase genes and down regulates virulence-associated surface lipid synthesis.
Submit: New GeneRIF Correction

Homology

Preferred Names
ECF RNA polymerase sigma factor SigM

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    4400186..4400854
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218428.1 ECF RNA polymerase sigma factor SigM [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218428.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M8L2
    Conserved Domains (2) summary
    PRK09643
    Location:5 → 184
    PRK09643; RNA polymerase sigma factor SigM; Reviewed
    pfam04542
    Location:39 → 105
    Sigma70_r2; Sigma-70 region 2
Nucleotide Protein
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