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mycP1 membrane-anchored mycosin [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886217, updated on 6-Jun-2024
Gene symbol
mycP1
Gene description
membrane-anchored mycosin
Locus tag
Rv3883c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
snm8
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Sequence:
NC_000962.3 (4363417..4364757, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene ESX-1 secretion-associated protein EspK Neighboring gene ESX-1 secretion-associated protein EspL Neighboring gene ESX-1 secretion-associated protein EspB Neighboring gene ESX-1 secretion system protein EccE1 Neighboring gene ESX-2 secretion system protein EccA Neighboring gene ESX-2 secretion system protein EccE Neighboring gene membrane-anchored mycosin

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence. Ohol YM, et al. Cell Host Microbe, 2010 Mar 18. PMID 20227664, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MycP1 is required for growth in mice during acute infection, while loss of its protease activity leads to attenuated virulence during chronic infection.
    Title: Mycobacterium tuberculosis MycP1 protease plays a dual role in regulation of ESX-1 secretion and virulence.
Submit: New GeneRIF Correction

Homology

Preferred Names
membrane-anchored mycosin
NP_218400.1
  • MycP1 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-1)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    4363417..4364757 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218400.1 membrane-anchored mycosin [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218400.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q7D4N8
    Conserved Domains (1) summary
    TIGR03921
    Location:70 → 446
    T7SS_mycosin; type VII secretion-associated serine protease mycosin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O05461.1

Gene LinkOut

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Molecular Biology Databases
Research Materials