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eccA1 ESX-1 secretion system protein EccA1 [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886199, updated on 6-Jun-2024
Gene symbol
eccA1
Gene description
ESX-1 secretion system protein EccA1
Locus tag
Rv3868
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (4343314..4345035)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene ESX-1 secretion-associated protein EspF Neighboring gene ESX-1 secretion-associated protein EspG Neighboring gene ESX-1 secretion-associated protein EspH Neighboring gene ESX-1 secretion system protein EccB Neighboring gene ESX-1 secretion system protein EccCa

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria. Champion PA, et al. Mol Microbiol, 2009 Sep. PMID 19682254, Free PMC Article
  2. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. McLaughlin B, et al. PLoS Pathog, 2007 Aug 3. PMID 17676952, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The authors show that the EspC substrate interacts with Rv3868, a cytosolic AAA ATPase, through its C-terminus.
    Title: ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria.
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Homology

Preferred Names
ESX-1 secretion system protein EccA1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    4343314..4345035
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218385.1 ESX-1 secretion system protein EccA1 [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218385.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M3W5
    Conserved Domains (1) summary
    TIGR03922
    Location:27 → 566
    T7SS_EccA; type VII secretion AAA-ATPase EccA
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WPH9.1

Gene LinkOut

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Research Materials