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ethA monooxygenase EthA [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886175, updated on 6-Oct-2023
Gene symbol
ethA
Gene description
monooxygenase EthA
Locus tag
Rv3854c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
aka; etaA
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Try the new Transcripts and proteins table
Sequence:
NC_000962.3 (4326004..4327473, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene histone-like protein Hns Neighboring gene RNase E regulator RraA Neighboring gene HTH-type transcriptional repressor EthR Neighboring gene hypothetical protein

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Whole-Transcriptome and -Genome Analysis of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates Identifies Downregulation of ethA as a Mechanism of Ethionamide Resistance. de Welzen L, et al. Antimicrob Agents Chemother, 2017 Dec. PMID 28993337, Free PMC Article
  2. Genotypic Analysis of Genes Associated with Independent Resistance and Cross-Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis Clinical Isolates. Rueda J, et al. Antimicrob Agents Chemother, 2015 Dec. PMID 26369965, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Whole-transcriptome and -genome analysis of extensively drug-resistant Mycobacterium tuberculosis clinical isolates identifies downregulation of ethA as a mechanism of ethionamide resistance.
    Title: Whole-Transcriptome and -Genome Analysis of Extensively Drug-Resistant Mycobacterium tuberculosis Clinical Isolates Identifies Downregulation of ethA as a Mechanism of Ethionamide Resistance.
  2. The greatest rate of mutations causing ethionamide resistance were observed in katG, ethA, in mshA.
    Title: Genotypic Analysis of Genes Associated with Independent Resistance and Cross-Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis Clinical Isolates.
Submit: New GeneRIF Correction

Homology

Preferred Names
monooxygenase EthA
NP_218371.1
  • FAD-containing

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    4326004..4327473 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218371.1 monooxygenase EthA [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218371.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A077D4A4, A0A077D8N2, A0A346TEP3, E7CT47, E7CT48, E7CT51, E7CT55
    Conserved Domains (1) summary
    COG2072
    Location:1 → 447
    CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WNF9.1

Gene LinkOut

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Research Materials