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pheA prephenate dehydratase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886170, updated on 11-Dec-2020

Summary

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Gene symbol
pheA
Gene description
prephenate dehydratase
Locus tag
Rv3838c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (4311704..4312669, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene phosphoglycerate mutase Neighboring gene hypothetical protein Neighboring gene transcriptional regulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural studies of prephenate dehydratase from Mycobacterium tuberculosis H37Rv by SAXS, ultracentrifugation, and computational analysis. Vivan AL, et al. Proteins, 2008 Sep. PMID 18384085
  2. Crystallization and preliminary X-ray diffraction analysis of prephenate dehydratase from Mycobacterium tuberculosis H37Rv. Vivan AL, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2006 Apr 1. PMID 16582484, Free PMC Article
  3. pheA (Rv3838c) of Mycobacterium tuberculosis encodes an allosterically regulated monofunctional prephenate dehydratase that requires both catalytic and regulatory domains for optimum activity. Prakash P, et al. J Biol Chem, 2005 May 27. PMID 15753077
  4. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  5. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The structure prephenate dehydratase in solution was studied.
    Title: Structural studies of prephenate dehydratase from Mycobacterium tuberculosis H37Rv by SAXS, ultracentrifugation, and computational analysis.
  2. results provide evidence for a monofunctional prephenate dehydratase enzyme from Mycobacterium tuberculosis that exhibits allosteric activation by aromatic amino acids and is dependent upon catalytic as well as the regulatory domains for enzyme activity
    Title: pheA (Rv3838c) of Mycobacterium tuberculosis encodes an allosterically regulated monofunctional prephenate dehydratase that requires both catalytic and regulatory domains for optimum activity.
  3. M. tuberculosis prephenate dehydratase has been cloned, expressed, purified and crystallized by the hanging-drop vapour-diffusion method using PEG 400 as a precipitant
    Title: Crystallization and preliminary X-ray diffraction analysis of prephenate dehydratase from Mycobacterium tuberculosis H37Rv.
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Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
prephenate dehydratase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    4311704..4312669 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_218355.1 prephenate dehydratase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_218355.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    PRK11898
    Location:1 → 281
    PRK11898; prephenate dehydratase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WIC3.1

Gene LinkOut

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