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bfrA bacterioferritin BfrA [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 885767, updated on 6-Oct-2023

Summary

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Gene symbol
bfrA
Gene description
bacterioferritin BfrA
Locus tag
Rv1876
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
bfr
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Genomic context

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Sequence:
NC_000962.3 (2125340..2125819)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene MFS-type transporter Neighboring gene glutamine synthetase GlnA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of Bfr A from Mycobacterium tuberculosis: incorporation of selenomethionine results in cleavage and demetallation of haem. Gupta V, et al. PLoS One, 2009 Nov 25. PMID 19946376, Free PMC Article
  2. Iron storage proteins are essential for the survival and pathogenesis of Mycobacterium tuberculosis in THP-1 macrophages and the guinea pig model of infection. Reddy PV, et al. J Bacteriol, 2012 Feb. PMID 22101841, Free PMC Article
  3. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  4. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  5. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BfrA and bfrB are essential for the survival and pathogenesis of Mycobacterium tuberculosis in THP-1 macrophages.
    Title: Iron storage proteins are essential for the survival and pathogenesis of Mycobacterium tuberculosis in THP-1 macrophages and the guinea pig model of infection.
  2. incorporation of selenomethionine results in cleavage and demetallation of heme in Mycobacterium tuberculosis BfrA
    Title: Crystal structure of Bfr A from Mycobacterium tuberculosis: incorporation of selenomethionine results in cleavage and demetallation of haem.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
bacterioferritin BfrA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    2125340..2125819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216392.1 bacterioferritin BfrA [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216392.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4LYF3
    Conserved Domains (1) summary
    TIGR00754
    Location:1 → 157
    bfr; bacterioferritin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WPQ9.1

Gene LinkOut

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