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FCGBP Fc fragment of IgG binding protein [ Homo sapiens (human) ]

Gene ID: 8857, updated on 6-Sep-2021

Summary

Official Symbol
FCGBPprovided by HGNC
Official Full Name
Fc fragment of IgG binding proteinprovided by HGNC
Primary source
HGNC:HGNC:13572
See related
Ensembl:ENSG00000275395 MIM:617553
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FC(GAMMA)BP
Annotation information
Annotation category: spans an assembly gap
Annotation category: partial on reference assembly
Expression
Biased expression in colon (RPKM 352.9), thyroid (RPKM 129.4) and 4 other tissues See more
Orthologs
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Genomic context

See FCGBP in Genome Data Viewer
Location:
19q13.2
Exon count:
32
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (39863323..39934626, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (40353963..40440533, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene dual specificity tyrosine phosphorylation regulated kinase 1B Neighboring gene microRNA 6719 Neighboring gene fibrillarin Neighboring gene uncharacterized LOC107987267 Neighboring gene proline rich 13 pseudogene 5 Neighboring gene proteasome 26S subunit, ATPase 4

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
is_active_in extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
IgGFc-binding protein
Names
Human Fc gamma BP
IgG Fc binding protein
fcgamma-binding protein antigen
fcgammaBP

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_003890.2NP_003881.2  IgGFc-binding protein precursor

    See identical proteins and their annotated locations for NP_003881.2

    Status: VALIDATED

    Source sequence(s)
    AC007842, AC011536, BE294466, BM781647, BQ065661, BU731683, BX113070, CD617655, D84239
    UniProtKB/Swiss-Prot
    Q9Y6R7
    Related
    ENSP00000481056.3, ENST00000616721.6
    Conserved Domains (5) summary
    smart00832
    Location:667742
    C8; This domain contains 8 conserved cysteine residues
    pfam00094
    Location:472627
    VWD; von Willebrand factor type D domain
    pfam01826
    Location:23372390
    TIL; Trypsin Inhibitor like cysteine rich domain
    cl02516
    Location:52355382
    VWD; von Willebrand factor type D domain
    cl17735
    Location:11941245
    VWC; von Willebrand factor type C domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    39863323..39934626 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 PATCHES

Genomic

  1. NW_009646206.1 Reference GRCh38.p13 PATCHES

    Range
    123199..209769 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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