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purN phosphoribosylglycinamide formyltransferase PurN [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 885407, updated on 6-Oct-2023

Summary

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Gene symbol
purN
Gene description
phosphoribosylglycinamide formyltransferase PurN
Locus tag
Rv0956
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (1067561..1068208)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene transmembrane protein Neighboring gene integral membrane protein Neighboring gene bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosinemonophosphate cyclohydrolase Neighboring gene magnesium chelatase Neighboring gene hypothetical protein Neighboring gene antitoxin VapB9 Neighboring gene ribonuclease VapC9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery. Zhang Z, et al. J Mol Biol, 2009 Jun 19. PMID 19394344
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results describe the structure of M. tuberculosis PurN in complex with magnesium and iodide at 1.30 A resolution, and with cofactor analogue, 5-methyltetrahydrofolate at 2.2 A resolution.
    Title: Structures of glycinamide ribonucleotide transformylase (PurN) from Mycobacterium tuberculosis reveal a novel dimer with relevance to drug discovery.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
phosphoribosylglycinamide formyltransferase PurN
NP_215471.1
  • GART (gar transformylase) (5'-phosphoribosylglycinamide transformylase)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1067561..1068208
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215471.1 phosphoribosylglycinamide formyltransferase PurN [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215471.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4LVY6
    Conserved Domains (1) summary
    PRK05647
    Location:12 → 209
    purN; phosphoribosylglycinamide formyltransferase; Reviewed
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WHM5.1

Gene LinkOut

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Molecular Biology Databases