U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosinemonophosphate cyclohydrolase [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 885406, updated on 6-Oct-2023
Gene symbol
purH
Gene description
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosinemonophosphate cyclohydrolase
Locus tag
Rv0957
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_000962.3 (1068205..1069776)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene transmembrane protein Neighboring gene integral membrane protein Neighboring gene phosphoribosylglycinamide formyltransferase PurN Neighboring gene magnesium chelatase Neighboring gene hypothetical protein Neighboring gene antitoxin VapB9 Neighboring gene ribonuclease VapC9

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide. Le Nours J, et al. J Biol Chem, 2011 Nov 25. PMID 21956117, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. the crystal structures of the M. tuberculosis ATIC (Rv0957) both with and without the substrate 5-aminoimidazole-4-carboxamide ribonucleotide
    Title: Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide.
Submit: New GeneRIF Correction

Homology

Preferred Names
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosinemonophosphate cyclohydrolase
NP_215472.1
  • PurH, bifunctional purine biosynthesis protein including 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase and inosine-monophosphate (imp) cyclohydrolase

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1068205..1069776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215472.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosinemonophosphate cyclohydrolase [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215472.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A654ZTP0
    Conserved Domains (1) summary
    PRK00881
    Location:7 → 523
    purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
3ZZM_A.1
3ZZM_B.1
4A1O_A.1
4A1O_B.1
P9WHM7.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials