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vapC12 ribonuclease VapC12 [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 885180, updated on 10-Feb-2026
Gene symbol
vapC12
Gene description
ribonuclease VapC12
Locus tag
Rv1720c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Sequence:
NC_000962.3 (1947030..1947419, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene transcriptional regulator Neighboring gene tRNA-Pro Neighboring gene antitoxin VapB12 Neighboring gene carboxylase Neighboring gene hydrolase Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. VapC12 ribonuclease toxin modulates host immune response during Mycobacterium tuberculosis infection. Tyagi S, et al. Front Immunol, 2024. PMID 38515752, Free PMC Article
  2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. VapC12 ribonuclease toxin modulates host immune response during Mycobacterium tuberculosis infection.
    Title: VapC12 ribonuclease toxin modulates host immune response during Mycobacterium tuberculosis infection.
Submit: New GeneRIF Correction

Homology

Preferred Names
ribonuclease VapC12
NP_216236.1
  • toxin, part of toxin-antitoxin (TA) operon with Rv1721c, contains PIN domain

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1947030..1947419 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_216236.1 ribonuclease VapC12 [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_216236.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2I7W7D7
    Conserved Domains (1) summary
    COG4113
    Location:1 → 128
    COG4113; Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WFA3.1

Gene LinkOut

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Molecular Biology Databases