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lipA lactonizing lipase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 882662, updated on 24-Aug-2024
Gene symbol
lipA
Gene description
lactonizing lipase
Locus tag
PA2862
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Sequence:
NC_002516.2 (3214282..3215217)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene 2'-5' RNA ligase Neighboring gene lipase chaperone Neighboring gene hypothetical protein

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation. Viegas A, et al. Sci Rep, 2020 Feb 27. PMID 32107397, Free PMC Article
  2. Purification of extracellular lipase from Pseudomonas aeruginosa. Stuer W, et al. J Bacteriol, 1986 Dec. PMID 3096967, Free PMC Article
  3. Bacterial lipases. Jaeger KE, et al. FEMS Microbiol Rev, 1994 Sep. PMID 7946464
  4. Purification and properties of extracellular lipase from Pseudomonas aeruginosa EF2. Gilbert EJ, et al. J Gen Microbiol, 1991 Sep. PMID 1748875
  5. The lipase LipA (PA2862) but not LipC (PA4813) from Pseudomonas aeruginosa influences regulation of pyoverdine production and expression of the sigma factor PvdS. Funken H, et al. J Bacteriol, 2011 Oct. PMID 21840975, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation.
    Title: Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation.
  2. In conclusion, this study for the first time indicates that AlgR directly binds to rsmZ to regulates the expression of lipA via regulating transcription of rsmZ, and mainly regulates the expression of lipA at transcriptional level in P. protegens Pf-5.
    Title: The Pseudomonas transcriptional regulator AlgR controls LipA expression via the noncoding RNA RsmZ in Pseudomonas protegens Pf-5.
  3. The LipA (PA2862) but not LipC (PA4813) influences regulation of pyoverdine production and expression of the sigma factor PvdS.
    Title: The lipase LipA (PA2862) but not LipC (PA4813) from Pseudomonas aeruginosa influences regulation of pyoverdine production and expression of the sigma factor PvdS.
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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables lipase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within protein secretion by the type II secretion system IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein transport by the Sec complex IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
lactonizing lipase
NP_251552.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    3214282..3215217
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_251552.1 lactonizing lipase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_251552.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q9L6C7
    Conserved Domains (1) summary
    COG1075
    Location:1 → 308
    EstA; Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P26876.2

Gene LinkOut

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Molecular Biology Databases
Research Materials