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wbpB UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 882642, updated on 24-Sep-2023

Summary

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Gene symbol
wbpB
Gene description
UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase
Locus tag
PA3158
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (3542740..3543690, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase Neighboring gene UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronate N-acetyltransferase Neighboring gene acetyltransferase Neighboring gene UDP-N-acetyl-d-glucosamine 6-dehydrogenase Neighboring gene O-antigen chain length regulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1. Larkin A, et al. Biochemistry, 2009 Jun 16. PMID 19348502, Free PMC Article
  2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
  5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB enzyme in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1
    Title: Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes in the Wbp pathway responsible for O-antigen assembly in Pseudomonas aeruginosa PAO1.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables NADH dehydrogenase activity EXP
Inferred from Experiment
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within O antigen biosynthetic process EXP
Inferred from Experiment
more info
 PubMed 
acts_upstream_of_or_within UDP-glucuronate biosynthetic process EXP
Inferred from Experiment
more info
 PubMed 
acts_upstream_of_or_within polysaccharide biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase
NP_251848.1
  • Product name confidence: class 1: Function experimentally demonstrated in P. aeruginosa

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    3542740..3543690 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_251848.1 UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_251848.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    G3XD23
    Conserved Domains (2) summary
    pfam01408
    Location:2 → 125
    GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold
    pfam02894
    Location:150 → 309
    GFO_IDH_MocA_C; Oxidoreductase family, C-terminal alpha/beta domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
G3XD23.1

Gene LinkOut

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Molecular Biology Databases
Research Materials