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pvdQ acyl-homoserine lactone acylase PvdQ [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 882260, updated on 6-Jul-2026
Gene symbol
pvdQ
Gene description
acyl-homoserine lactone acylase PvdQ
Locus tag
PA2385
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Sequence:
NC_002516.2 (2636517..2638805, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene transcriptional regulator Neighboring gene hypothetical protein Neighboring gene L-ornithine N5-oxygenase Neighboring gene RNA polymerase sigma factor

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Influence of Pseudomonas aeruginosa pvdQ gene on altering antibiotic susceptibility under swarming conditions. Wang L, et al. Curr Microbiol, 2011 Oct. PMID 21833667
  2. Pseudomonas aeruginosa pvdQ gene prevents Caco-2 cells from obstruction of quorum-sensing signal. Ye L, et al. Curr Microbiol, 2011 Jan. PMID 20490497
  3. The quorum-quenching N-acyl homoserine lactone acylase PvdQ is an Ntn-hydrolase with an unusual substrate-binding pocket. Bokhove M, et al. Proc Natl Acad Sci U S A, 2010 Jan 12. PMID 20080736, Free PMC Article
  4. Role of PvdQ in Pseudomonas aeruginosa virulence under iron-limiting conditions. Jimenez PN, et al. Microbiology (Reading), 2010 Jan. PMID 19778968
  5. Influence of Pseudomonas aeruginosa pvdQ gene on altering antibiotic susceptibility under swarming conditions. Wang L, et al. Curr Microbiol, 2013 Feb. PMID 23090643

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IDA
Inferred from Direct Assay
more info
 PubMed 
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in antibiotic biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in bacterial-type flagellum-dependent swarming motility IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in bacterial-type flagellum-dependent swarming motility IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pyoverdine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in pyoverdine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to antibiotic IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in single-species biofilm formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
acyl-homoserine lactone acylase PvdQ
NP_251075.1
  • class 1: Function experimentally demonstrated in P. aeruginosa

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    2636517..2638805 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_251075.1 acyl-homoserine lactone acylase PvdQ [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_251075.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    cd01936
    Location:35 → 744
    Ntn_CA; Cephalosporin acylase (CA) belongs to a family of beta-lactam acylases that includes penicillin G acylase (PGA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I194.1

Gene LinkOut

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Molecular Biology Databases