U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mucB sigma factor AlgU regulator MucB [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 882064, updated on 11-Sep-2024

Summary

Go to the top of the page Help
Gene symbol
mucB
Gene description
sigma factor AlgU regulator MucB
Locus tag
PA0764
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_002516.2 (832507..833457)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene RNA polymerase sigma factor AlgU Neighboring gene sigma factor AlgU negative regulator MucA Neighboring gene positive regulator for alginate biosynthesis MucC Neighboring gene serine protease MucD Neighboring gene elongation factor 4

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Posttranslational control of the algT (algU)-encoded sigma22 for expression of the alginate regulon in Pseudomonas aeruginosa and localization of its antagonist proteins MucA and MucB (AlgN). Mathee K, et al. J Bacteriol, 1997 Jun. PMID 9171421, Free PMC Article
  2. Molecular basis of the lipid-induced MucA-MucB dissociation in Pseudomonas aeruginosa. Li T, et al. Commun Biol, 2020 Aug 3. PMID 32747658, Free PMC Article
  3. Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa. Li S, et al. FEBS J, 2019 Dec. PMID 31297938
  4. Control of Pseudomonas aeruginosa AlgW protease cleavage of MucA by peptide signals and MucB. Cezairliyan BO, et al. Mol Microbiol, 2009 Apr. PMID 19298369, Free PMC Article
  5. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Molecular basis of the lipid-induced MucA-MucB dissociation in Pseudomonas aeruginosa.
    Title: Molecular basis of the lipid-induced MucA-MucB dissociation in Pseudomonas aeruginosa.
  2. The structures reveal the molecular basis for MucA recognition by MucB in the periplasm and AlgU in the cytoplasm, thus providing an important step in understanding the mechanisms that regulate a key signal transduction pathway involved in P. aeruginosa pathogenesis.
    Title: Structural basis for the recognition of MucA by MucB and AlgU in Pseudomonas aeruginosa.
  3. Binding of MucB to MucA inhibits MucA cleavage by AlgW.
    Title: Control of Pseudomonas aeruginosa AlgW protease cleavage of MucA by peptide signals and MucB.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by PseudoCAP

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of polysaccharide biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
sigma factor AlgU regulator MucB
NP_249455.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    832507..833457
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_249455.1 sigma factor AlgU regulator MucB [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_249455.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3M5D7D3
    Conserved Domains (1) summary
    COG3026
    Location:14 → 314
    RseB; Negative regulator of sigma E activity [Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38108.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases