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fabA 3-hydroxydecanoyl-ACP dehydratase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 881984, updated on 30-Jul-2025
Gene symbol
fabA
Gene description
3-hydroxydecanoyl-ACP dehydratase
Locus tag
PA1610
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Sequence:
NC_002516.2 (1752903..1753418, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene chemotaxis transducer Neighboring gene 3-oxoacyl-ACP synthase Neighboring gene sensor/response regulator hybrid protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Characterization of molecular mechanisms controlling fabAB transcription in Pseudomonas aeruginosa. Schweizer HP, et al. PLoS One, 2012. PMID 23056212, Free PMC Article
  2. Fatty acid biosynthesis in Pseudomonas aeruginosa: cloning and characterization of the fabAB operon encoding beta-hydroxyacyl-acyl carrier protein dehydratase (FabA) and beta-ketoacyl-acyl carrier protein synthase I (FabB). Hoang TT, et al. J Bacteriol, 1997 Sep. PMID 9286984, Free PMC Article
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data suggest a promoter requiring an activator for RNA polymerase binding to initiate fabAB transcription.
    Title: Characterization of molecular mechanisms controlling fabAB transcription in Pseudomonas aeruginosa.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables trans-2-decenoyl-acyl-carrier-protein isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in unsaturated fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in unsaturated fatty acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
3-hydroxydecanoyl-ACP dehydratase
NP_250301.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    1752903..1753418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_250301.1 3-hydroxydecanoyl-ACP dehydratase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_250301.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O33877
    Conserved Domains (1) summary
    PRK05174
    Location:1 → 171
    PRK05174; bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O33877.1

Gene LinkOut

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Molecular Biology Databases
Research Materials