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cueR protein CueR [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 881842, updated on 24-Aug-2024

Summary

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Gene symbol
cueR
Gene description
protein CueR
Locus tag
PA4778
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (5366257..5366655)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene two-component regulator system response regulator PmrA Neighboring gene two-component regulator system signal sensor kinase PmrB Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa. Novoa-Aponte L, et al. J Biol Chem, 2019 Mar 29. PMID 30718281, Free PMC Article
  2. Structural characterizations of metal ion binding transcriptional regulator CueR from opportunistic pathogen pseudomonas aeruginosa to identify its possible involvements in virulence. Bagchi A. Appl Biochem Biotechnol, 2015 Jan. PMID 25342258
  3. Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa. Thaden JT, et al. J Bacteriol, 2010 May. PMID 20233934, Free PMC Article
  4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa.
    Title: The interplay of the metallosensor CueR with two distinct CopZ chaperones defines copper homeostasis in Pseudomonas aeruginosa.
  2. The expression of PA3523 is regulated by the dimeric transcription factor CueR having helix-turn-helix DNA binding motif.
    Title: Structural characterizations of metal ion binding transcriptional regulator CueR from opportunistic pathogen pseudomonas aeruginosa to identify its possible involvements in virulence.
  3. Work identifies a cellular function for PA4778 and four other previously unannotated genes (PA3515, PA3516, PA3517, and PA3518) and suggests a potential role for copper in the quorum response. Study propose to name PA4778 cueR.
    Title: Quorum-sensing regulation of a copper toxicity system in Pseudomonas aeruginosa.
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General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
protein CueR
NP_253466.1
  • Product name confidence: class 1: Function experimentally demonstrated in P. aeruginosa

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    5366257..5366655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_253466.1 protein CueR [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_253466.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    cd01108
    Location:1 → 127
    HTH_CueR; Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9HV30.1

Gene LinkOut

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Molecular Biology Databases
Research Materials