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folP dihydropteroate synthase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 881715, updated on 24-Aug-2024
Gene symbol
folP
Gene description
dihydropteroate synthase
Locus tag
PA4750
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Sequence:
NC_002516.2 (5334921..5335772, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene triosephosphate isomerase Neighboring gene phosphoglucosamine mutase Neighboring gene cell division protein FtsH Neighboring gene cell division protein FtsJ

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Cloning, sequencing, and enhanced expression of the dihydropteroate synthase gene of Escherichia coli MC4100. Dallas WS, et al. J Bacteriol, 1992 Sep. PMID 1522070, Free PMC Article
  2. Purification and partial characterization of 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase and 7,8-dihydropteroate synthase from Escherichia coli MC4100. Talarico TL, et al. J Bacteriol, 1991 Nov. PMID 1657875, Free PMC Article
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables dihydropteroate synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables dihydropteroate synthase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within folic acid biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Preferred Names
dihydropteroate synthase
NP_253438.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    5334921..5335772 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_253438.1 dihydropteroate synthase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_253438.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3M5EE89
    Conserved Domains (1) summary
    cl00219
    Location:15 → 282
    Pterin_binding; Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH). DHPS, a ...
Nucleotide Protein
Heading Accession and Version

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