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folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 881616, updated on 11-Sep-2024

Summary

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Gene symbol
folK
Gene description
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Locus tag
PA4728
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (5310726..5311214)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene poly(A) polymerase Neighboring gene 3-methyl-2-oxobutanoate hydroxymethyltransferase Neighboring gene pantoate--beta-alanine ligase Neighboring gene aspartate alpha-decarboxylase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning, sequence analysis, and overexpression of Escherichia coli folK, the gene coding for 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. Talarico TL, et al. J Bacteriol, 1992 Sep. PMID 1325970, Free PMC Article
  2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
  5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NP_253416.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    5310726..5311214
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_253416.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_253416.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9HV71
    Conserved Domains (1) summary
    COG0801
    Location:3 → 160
    FolK; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9HV71.1

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