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CCIN calicin [ Homo sapiens (human) ]

Gene ID: 881, updated on 18-Aug-2020

Summary

Official Symbol
CCINprovided by HGNC
Official Full Name
calicinprovided by HGNC
Primary source
HGNC:HGNC:1568
See related
Ensembl:ENSG00000185972 MIM:603960
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BTBD20; KBTBD14
Summary
The protein encoded by this gene is a basic protein of the sperm head cytoskeleton. This protein contains kelch repeats and a BTB/POZ domain and is necessary for normal morphology during sperm differentiation. This gene is intronless. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See CCIN in Genome Data Viewer
Location:
9p13.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (36169388..36171334)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (36165990..36171331)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene reversion inducing cysteine rich protein with kazal motifs Neighboring gene GLI pathogenesis related 2 Neighboring gene clathrin light chain A Neighboring gene glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Neighboring gene uncharacterized LOC102724322 Neighboring gene RNA, U4 small nuclear 53, pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
brain development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeletal calyx IEA
Inferred from Electronic Annotation
more info
 
dendrite cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus HDA PubMed 

General protein information

Preferred Names
calicin
Names
testis tissue sperm-binding protein Li 65n

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005893.3NP_005884.2  calicin

    See identical proteins and their annotated locations for NP_005884.2

    Status: REVIEWED

    Source sequence(s)
    AK313763, AL158830, BC019251
    Consensus CDS
    CCDS6599.1
    UniProtKB/Swiss-Prot
    Q13939
    UniProtKB/TrEMBL
    Q8WWB2, Q8WX35
    Related
    ENSP00000334996.2, ENST00000335119.4
    Conserved Domains (7) summary
    smart00225
    Location:29128
    BTB; Broad-Complex, Tramtrack and Bric a brac
    smart00875
    Location:133234
    BACK; BTB And C-terminal Kelch
    sd00038
    Location:317362
    Kelch; KELCH repeat [structural motif]
    pfam00651
    Location:18125
    BTB; BTB/POZ domain
    pfam01344
    Location:366410
    Kelch_1; Kelch motif
    pfam13418
    Location:515568
    Kelch_4; Galactose oxidase, central domain
    pfam13964
    Location:321364
    Kelch_6; Kelch motif

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    36169388..36171334
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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