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popB translocator protein PopB [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 880867, updated on 24-Aug-2024
Gene symbol
popB
Gene description
translocator protein PopB
Locus tag
PA1708
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Sequence:
NC_002516.2 (1853665..1854837)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene type III secretion regulator Neighboring gene type III secretion protein PcrV Neighboring gene regulatory protein PcrH Neighboring gene translocator outer membrane protein PopD Neighboring gene exoenzyme S synthesis protein ExsC

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Type 3 Secretion Translocators Spontaneously Assemble a Hexadecameric Transmembrane Complex. Romano FB, et al. J Biol Chem, 2016 Mar 18. PMID 26786106, Free PMC Article
  2. Binding mode analysis of a major T3SS translocator protein PopB with its chaperone PcrH from Pseudomonas aeruginosa. Banerjee A, et al. Proteins, 2014 Dec. PMID 25116453
  3. Membrane and chaperone recognition by the major translocator protein PopB of the type III secretion system of Pseudomonas aeruginosa. Discola KF, et al. J Biol Chem, 2014 Feb 7. PMID 24297169, Free PMC Article
  4. Protein binding between PcrG-PcrV and PcrH-PopB/PopD encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion system. Allmond LR, et al. Infect Immun, 2003 Apr. PMID 12654846, Free PMC Article
  5. Functional conservation of the effector protein translocators PopB/YopB and PopD/YopD of Pseudomonas aeruginosa and Yersinia pseudotuberculosis. Frithz-Lindsten E, et al. Mol Microbiol, 1998 Sep. PMID 9767584

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The interaction between PopB and PopD guide the assembly of a unique hetero-oligomer in membranes.
    Title: Type 3 Secretion Translocators Spontaneously Assemble a Hexadecameric Transmembrane Complex.
  2. Data suggest that PscH participates in Type III secretion system for PopB; binding sites on PcrH for PopB are primarily localized within N-terminal domain; disordered/flexible residues at N- and C-terminal domains are also involved.
    Title: Binding mode analysis of a major T3SS translocator protein PopB with its chaperone PcrH from Pseudomonas aeruginosa.
  3. the crystal structure of the complex between PcrH and an N-terminal region of PopB (residues 51-59), which reveals that PopB lies within the concave face of PcrH, employing mostly backbone residues for contact.
    Title: Membrane and chaperone recognition by the major translocator protein PopB of the type III secretion system of Pseudomonas aeruginosa.
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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables protein-folding chaperone binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within translocation of peptides or proteins into host IGI
Inferred from Genetic Interaction
more info
 PubMed 
Preferred Names
translocator protein PopB
NP_250399.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    1853665..1854837
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_250399.1 translocator protein PopB [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_250399.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    O30529
    Conserved Domains (1) summary
    COG5613
    Location:1 → 390
    COG5613; Uncharacterized protein [Function unknown]
Nucleotide Protein
Heading Accession and Version

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