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lpxD UDP-3-O-acylglucosamine N-acyltransferase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 880525, updated on 11-Sep-2024

Summary

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Gene symbol
lpxD
Gene description
UDP-3-O-acylglucosamine N-acyltransferase
Locus tag
PA3646
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (4083444..4084505, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene ribonuclease HII Neighboring gene lipid-A-disaccharide synthase Neighboring gene acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase Neighboring gene 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ Neighboring gene hypothetical protein Neighboring gene outer membrane protein Opr86

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of the lipopolysaccharide biosynthesis gene lpxD affects biofilm formation of Pseudomonas aeruginosa. Alshalchi SA, et al. Arch Microbiol, 2015 Mar. PMID 25173672
  2. The novel hexapeptide motif found in the acyltransferases LpxA and LpxD of lipid A biosynthesis is conserved in various bacteria. Vuorio R, et al. FEBS Lett, 1994 Jan 17. PMID 8293817
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables acyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within lipid A biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
UDP-3-O-acylglucosamine N-acyltransferase
NP_252336.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    4083444..4084505 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_252336.1 UDP-3-O-acylglucosamine N-acyltransferase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_252336.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9HXY6
    Conserved Domains (1) summary
    PRK00892
    Location:6 → 341
    lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9HXY6.1

Gene LinkOut

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Molecular Biology Databases