U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

xcpQ type II secretion system protein D [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 880114, updated on 6-Jul-2026
Gene symbol
xcpQ
Gene description
type II secretion system protein D
Locus tag
PA3105
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_002516.2 (3484354..3486330)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene type II secretion system protein F Neighboring gene type II secretion system protein E Neighboring gene type II secretion system protein N Neighboring gene oxidoreductase Neighboring gene O-succinylhomoserine sulfhydrylase Neighboring gene amidophosphoribosyltransferase

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Xylose-Inducible Promoter Tools for Pseudomonas Species and Their Use in Implicating a Role for the Type II Secretion System Protein XcpQ in the Inhibition of Corneal Epithelial Wound Closure. Callaghan JD, et al. Appl Environ Microbiol, 2020 Jul 2. PMID 32414795, Free PMC Article
  2. Independent domain assembly in a trapped folding intermediate of multimeric outer membrane secretins. Guilvout I, et al. Structure, 2014 Apr 8. PMID 24657091
  3. Formation of oligomeric rings by XcpQ and PilQ, which are involved in protein transport across the outer membrane of Pseudomonas aeruginosa. Bitter W, et al. Mol Microbiol, 1998 Jan. PMID 9466268
  4. Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics. Douzi B, et al. mBio, 2017 Oct 17. PMID 29042493, Free PMC Article
  5. GSP-dependent protein secretion in gram-negative bacteria: the Xcp system of Pseudomonas aeruginosa. Filloux A, et al. FEMS Microbiol Rev, 1998 Sep. PMID 9818381

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Xylose-Inducible Promoter Tools for Pseudomonas Species and Their Use in Implicating a Role for the Type II Secretion System Protein XcpQ in the Inhibition of Corneal Epithelial Wound Closure.
    Title: Xylose-Inducible Promoter Tools for Pseudomonas Species and Their Use in Implicating a Role for the Type II Secretion System Protein XcpQ in the Inhibition of Corneal Epithelial Wound Closure.
  2. Here, the authors revealed that the N-terminal domain of XcpQ secretin spontaneously self-assembled into a hexamer of dimers independently of its C-terminal domain.
    Title: Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein secretion IEA
Inferred from Electronic Annotation
more info
  
involved_in protein secretion by the type II secretion system IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein secretion by the type II secretion system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein secretion by the type II secretion system IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in outer membrane IEA
Inferred from Electronic Annotation
more info
  
part_of type II protein secretion system complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of type II protein secretion system complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of type II protein secretion system complex IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
type II secretion system protein D
NP_251795.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    3484354..3486330
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_251795.1 type II secretion system protein D [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_251795.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    COG1450
    Location:20 → 645
    PulD; Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, and vesicular transport]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P35818.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases