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fpr ferredoxin-NADP reductase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 879913, updated on 30-Jul-2025
Gene symbol
fpr
Gene description
ferredoxin-NADP reductase
Locus tag
PA3397
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Sequence:
NC_002516.2 (3802567..3803343, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene copper ABC transporter ATP-binding protein Neighboring gene membrane protein NosY Neighboring gene acessory protein NosL Neighboring gene transcriptional regulator Neighboring gene hypothetical protein

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. X-ray crystallographic and solution state nuclear magnetic resonance spectroscopic investigations of NADP+ binding to ferredoxin NADP reductase from Pseudomonas aeruginosa. Wang A, et al. Biochemistry, 2008 Aug 5. PMID 18605699, Free PMC Article
  2. Biochemical and structural characterization of Pseudomonas aeruginosa Bfd and FPR: ferredoxin NADP+ reductase and not ferredoxin is the redox partner of heme oxygenase under iron-starvation conditions. Wang A, et al. Biochemistry, 2007 Oct 30. PMID 17915950
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Findings suggest a possible stepwise electron-proton-electron transfer of hydride in the oxidation of NADPH by FPR enzymes.
    Title: X-ray crystallographic and solution state nuclear magnetic resonance spectroscopic investigations of NADP+ binding to ferredoxin NADP reductase from Pseudomonas aeruginosa.
  2. Biochemical investigations demonstrated that the bfd gene encodes a 73-amino acid protein that incorporates a [2Fe-2S] center, whereas the fpr gene encodes a 258-residue NADPH-dependent ferredoxin reductase that utilizes FAD as a cofactor
    Title: Biochemical and structural characterization of Pseudomonas aeruginosa Bfd and FPR: ferredoxin NADP+ reductase and not ferredoxin is the redox partner of heme oxygenase under iron-starvation conditions.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables ferredoxin-NADP+ reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in heme catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
ferredoxin-NADP reductase
NP_252087.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    3802567..3803343 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_252087.1 ferredoxin-NADP reductase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_252087.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3M5DAI6
    Conserved Domains (1) summary
    cd06195
    Location:8 → 254
    FNR1; Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently ...
Nucleotide Protein
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