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oprG outer membrane protein OprG [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 879793, updated on 30-Jul-2025
Gene symbol
oprG
Gene description
outer membrane protein OprG
Locus tag
PA4067
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Sequence:
NC_002516.2 (4544607..4545305)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene epimerase Neighboring gene hypothetical protein Neighboring gene FeaR family transcriptional regulator

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Quaternary structure of the small amino acid transporter OprG from Pseudomonas aeruginosa. Sanganna Gari RR, et al. J Biol Chem, 2018 Nov 2. PMID 30237175, Free PMC Article
  2. The crystal structure of OprG from Pseudomonas aeruginosa, a potential channel for transport of hydrophobic molecules across the outer membrane. Touw DS, et al. PLoS One, 2010 Nov 29. PMID 21124774, Free PMC Article
  3. The major outer membrane protein OprG of Pseudomonas aeruginosa contributes to cytotoxicity and forms an anaerobically regulated, cation-selective channel. McPhee JB, et al. FEMS Microbiol Lett, 2009 Jun. PMID 19486157
  4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. OprG functions as an oligomer and that conformational changes in the barrel-loop region might be crucial for its activity.
    Title: Quaternary structure of the small amino acid transporter OprG from Pseudomonas aeruginosa.
  2. Data show that OprG forms an eight-stranded beta-barrel with a hydrophobic channel that leads from the extracellular surface to a lateral opening in the barrel wall.
    Title: The crystal structure of OprG from Pseudomonas aeruginosa, a potential channel for transport of hydrophobic molecules across the outer membrane.
  3. In the absence of OprG, P. aeruginosa was significantly less cytotoxic toward human bronchial epithelial cells.
    Title: The major outer membrane protein OprG of Pseudomonas aeruginosa contributes to cytotoxicity and forms an anaerobically regulated, cation-selective channel.
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Homology

Gene Ontology Provided by PseudoCAP

Process Evidence Code Pubs
involved_in transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in host outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in outer membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
outer membrane protein OprG
NP_252756.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    4544607..4545305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_252756.1 outer membrane protein OprG [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_252756.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3M5DDU1
    Conserved Domains (1) summary
    pfam03922
    Location:28 → 232
    OmpW; OmpW family
Nucleotide Protein
Heading Accession and Version

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