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algA bifunctional mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 879142, updated on 23-Apr-2026
Gene symbol
algA
Gene description
bifunctional mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase
Locus tag
PA3551
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Try the new Transcripts and proteins table
Sequence:
NC_002516.2 (3978031..3979476)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene alginate o-acetylase AlgJ Neighboring gene alginate o-acetyltransferase AlgF Neighboring gene UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase Neighboring gene undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase Neighboring gene bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase Neighboring gene 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Purification and characterization of phosphomannose isomerase-guanosine diphospho-D-mannose pyrophosphorylase. A bifunctional enzyme in the alginate biosynthetic pathway of Pseudomonas aeruginosa. Shinabarger D, et al. J Biol Chem, 1991 Feb 5. PMID 1846611
  2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
  5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables mannose-1-phosphate guanylyltransferase (GTP) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables mannose-1-phosphate guanylyltransferase (GTP) activity IEA
Inferred from Electronic Annotation
more info
  
enables mannose-6-phosphate isomerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables mannose-6-phosphate isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in GDP-mannose biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in alginic acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in polysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in polysaccharide metabolic process IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
bifunctional mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase
NP_252241.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    3978031..3979476
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_252241.1 bifunctional mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_252241.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    TIGR01479
    Location:1 → 468
    GMP_PMI; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P07874.3

Gene LinkOut

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Molecular Biology Databases