U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

putA bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 878503, updated on 30-Jul-2025
Gene symbol
putA
Gene description
bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase
Locus tag
PA0782
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_002516.2 (851783..854965)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene proline utilization regulator Neighboring gene hypothetical protein Neighboring gene sodium/proline symporter PutP Neighboring gene transcriptional regulator

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Purification and properties of the bifunctional proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase from Pseudomonas aeruginosa. Meile L, et al. Eur J Biochem, 1982 Dec. PMID 6819140
  2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
  5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables L-glutamate gamma-semialdehyde dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-glutamate gamma-semialdehyde dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables proline dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables proline dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-proline catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in L-proline catabolic process to L-glutamate IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in L-proline catabolic process to L-glutamate IEA
Inferred from Electronic Annotation
more info
  
involved_in proline metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase
NP_249473.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    851783..854965
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_249473.1 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_249473.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    PRK11904
    Location:8 → 1055
    PRK11904; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase PutA
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases