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clpX ATP-dependent protease ATP-binding subunit ClpX [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 878307, updated on 30-Jul-2025
Gene symbol
clpX
Gene description
ATP-dependent protease ATP-binding subunit ClpX
Locus tag
PA1802
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Try the new Transcripts and proteins table
Sequence:
NC_002516.2 (1954815..1956095)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene trigger factor Neighboring gene ATP-dependent Clp protease proteolytic subunit Neighboring gene Lon protease Neighboring gene DNA-binding protein HU

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus. Yang N, et al. Mol Microbiol, 2020 Sep. PMID 32323346
  2. ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa. Qiu D, et al. Microbiology (Reading), 2008 Jul. PMID 18599839, Free PMC Article
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus.
    Title: Alteration of protein homeostasis mediates the interaction of Pseudomonas aeruginosa with Staphylococcus aureus.
  2. The ClpXP and ClpP2 proteins degrades the cytoplasmic portion of truncated MucA proteins to release the sequestered AlgU, which drives alginate biosynthesis.
    Title: ClpXP proteases positively regulate alginate overexpression and mucoid conversion in Pseudomonas aeruginosa.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
ATP-dependent protease ATP-binding subunit ClpX
NP_250493.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    1954815..1956095
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_250493.1 ATP-dependent protease ATP-binding subunit ClpX [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_250493.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3M5DFV1
    Conserved Domains (1) summary
    PRK05342
    Location:5 → 417
    clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I2U0.1

Gene LinkOut

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Molecular Biology Databases