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bkdA1 2-oxoisovalerate dehydrogenase subunit alpha [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 877901, updated on 24-Aug-2024

Summary

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Gene symbol
bkdA1
Gene description
2-oxoisovalerate dehydrogenase subunit alpha
Locus tag
PA2247
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (2473213..2474445)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Bkd operon transcriptional regulator BkdR Neighboring gene 2-oxoisovalerate dehydrogenase subunit beta Neighboring gene branched-chain alpha-keto acid dehydrogenase complex lipoamide acyltransferase Neighboring gene branched-chain alpha-keto acid dehydrogenase complex dihydrolipoyl dehydrogenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  2. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  3. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
  4. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article
  5. Effect of anaerobiosis and nitrate on gene expression in Pseudomonas aeruginosa. Filiatrault MJ, et al. Infect Immun, 2005 Jun. PMID 15908409, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Process Evidence Code Pubs
acts_upstream_of_or_within oxoacid metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
2-oxoisovalerate dehydrogenase subunit alpha
NP_250937.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    2473213..2474445
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_250937.1 2-oxoisovalerate dehydrogenase subunit alpha [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_250937.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9I1M2
    Conserved Domains (2) summary
    COG1071
    Location:52 → 409
    AcoA; TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha [Energy production and conversion]
    pfam12573
    Location:5 → 45
    OxoDH_E1alpha_N; 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I1M2.1

Gene LinkOut

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Molecular Biology Databases