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dsbA thiol:disulfide interchange protein DsbA [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 877731, updated on 30-Jul-2025
Gene symbol
dsbA
Gene description
thiol:disulfide interchange protein DsbA
Locus tag
PA5489
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Sequence:
NC_002516.2 (6180942..6181577, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene cytochrome C4 Neighboring gene cytochrome

Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Characterization of the DsbA oxidative folding catalyst from Pseudomonas aeruginosa reveals a highly oxidizing protein that binds small molecules. Shouldice SR, et al. Antioxid Redox Signal, 2010 Apr 15. PMID 19788398
  2. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  3. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  4. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article
  5. A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. Salunkhe P, et al. J Bacteriol, 2005 Jul. PMID 15995206, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. study determined the 1.5 A resolution crystal structure of dsbA and characterized its redox properties; established that it is capable of binding small molecules
    Title: Characterization of the DsbA oxidative folding catalyst from Pseudomonas aeruginosa reveals a highly oxidizing protein that binds small molecules.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables disulfide oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
thiol:disulfide interchange protein DsbA
NP_254176.1
  • Product name confidence: class 2 (High similarity to functionally studied protein)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    6180942..6181577 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_254176.1 thiol:disulfide interchange protein DsbA [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_254176.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0C2B2
    Conserved Domains (1) summary
    cd03019
    Location:27 → 207
    DsbA_DsbA; DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0C2B2.1

Gene LinkOut

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