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MPDZ multiple PDZ domain crumbs cell polarity complex component [ Homo sapiens (human) ]

Gene ID: 8777, updated on 15-Sep-2022

Summary

Official Symbol
MPDZprovided by HGNC
Official Full Name
multiple PDZ domain crumbs cell polarity complex componentprovided by HGNC
Primary source
HGNC:HGNC:7208
See related
Ensembl:ENSG00000107186 MIM:603785; AllianceGenome:HGNC:7208
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HYC2; MUPP1
Summary
The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Expression
Ubiquitous expression in liver (RPKM 12.7), fat (RPKM 10.5) and 23 other tissues See more
Orthologs
NEW
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Genomic context

See MPDZ in Genome Data Viewer
Location:
9p23
Exon count:
56
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (13105707..13279692, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (13115022..13289090, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (13105706..13279691, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, C/D box 137 Neighboring gene peroxiredoxin 1 pseudogene 1 Neighboring gene lupus La protein-like Neighboring gene Sharpr-MPRA regulatory region 14432 Neighboring gene long intergenic non-protein coding RNA 1235 Neighboring gene uncharacterized LOC105375977

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Hydrocephalus, nonsyndromic, autosomal recessive 2
MedGen: C3554691 OMIM: 615219 GeneReviews: Not available
Compare labs

EBI GWAS Catalog

Description
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
EBI GWAS Catalog

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of multiple PDZ domain protein (MPDZ) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25909, FLJ34626, FLJ90240, DKFZp781P216

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein C-terminus binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in microtubule organizing center organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in apical part of cell IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in apicolateral plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
multiple PDZ domain protein
Names
multi-PDZ domain protein 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_042810.2 RefSeqGene

    Range
    5000..178985
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001261406.2NP_001248335.1  multiple PDZ domain protein isoform 2

    See identical proteins and their annotated locations for NP_001248335.1

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Consensus CDS
    CCDS59120.1
    UniProtKB/Swiss-Prot
    O75970
    Related
    ENSP00000415208.1, ENST00000447879.6
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:15291593
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  2. NM_001261407.2NP_001248336.1  multiple PDZ domain protein isoform 3

    See identical proteins and their annotated locations for NP_001248336.1

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Consensus CDS
    CCDS59119.1
    UniProtKB/Swiss-Prot
    O75970
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:15291593
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  3. NM_001330637.2NP_001317566.1  multiple PDZ domain protein isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Consensus CDS
    CCDS83342.1
    UniProtKB/Swiss-Prot
    O75970, Q8N790
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2; L27_2
    pfam16667
    Location:15621626
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  4. NM_001375413.1NP_001362342.1  multiple PDZ domain protein isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:15951659
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  5. NM_001375416.1NP_001362345.1  multiple PDZ domain protein isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:15291593
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  6. NM_001375417.1NP_001362346.1  multiple PDZ domain protein isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:15291593
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  7. NM_001375418.1NP_001362347.1  multiple PDZ domain protein isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:15291593
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  8. NM_001375419.1NP_001362348.1  multiple PDZ domain protein isoform 3

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Related
    ENSP00000444151.1, ENST00000536827.5
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:15291593
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  9. NM_001375420.1NP_001362349.1  multiple PDZ domain protein isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19161999
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:14921556
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  10. NM_001375421.1NP_001362350.1  multiple PDZ domain protein isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19161999
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:14921556
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  11. NM_001375422.1NP_001362351.1  multiple PDZ domain protein isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19161999
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:14921556
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  12. NM_001375423.1NP_001362352.1  multiple PDZ domain protein isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19161999
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:14921556
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  13. NM_001375424.1NP_001362353.1  multiple PDZ domain protein isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19161999
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:14921556
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  14. NM_001375425.1NP_001362354.1  multiple PDZ domain protein isoform 7

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:18871970
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:14921556
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  15. NM_001375426.1NP_001362355.1  multiple PDZ domain protein isoform 7

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:18871970
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:14921556
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  16. NM_001375427.1NP_001362356.1  multiple PDZ domain protein isoform 8

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:18501933
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:14261490
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  17. NM_001378778.1NP_001365707.1  multiple PDZ domain protein isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    UniProtKB/Swiss-Prot
    Q8N790
    Related
    ENSP00000320006.7, ENST00000319217.12
  18. NM_003829.5NP_003820.2  multiple PDZ domain protein isoform 1

    See identical proteins and their annotated locations for NP_003820.2

    Status: REVIEWED

    Source sequence(s)
    AL161449, AL162386, AL353639, KF458902
    Consensus CDS
    CCDS47951.1
    UniProtKB/Swiss-Prot
    O75970
    Related
    ENSP00000439807.1, ENST00000541718.5
    Conserved Domains (4) summary
    pfam09045
    Location:663
    L27_2; L27_2
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam16667
    Location:15621626
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    13105707..13279692 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047424033.1XP_047279989.1  multiple PDZ domain protein isoform X5

  2. XM_017015252.2XP_016870741.1  multiple PDZ domain protein isoform X2

  3. XM_006716888.4XP_006716951.1  multiple PDZ domain protein isoform X3

    See identical proteins and their annotated locations for XP_006716951.1

    UniProtKB/Swiss-Prot
    O75970
    Conserved Domains (4) summary
    pfam09045
    Location:663
    L27_2; L27_2
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam16667
    Location:15621626
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  4. XM_047424044.1XP_047280000.1  multiple PDZ domain protein isoform X8

  5. XM_047424016.1XP_047279972.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  6. XM_047424035.1XP_047279991.1  multiple PDZ domain protein isoform X6

  7. XM_006716886.4XP_006716949.1  multiple PDZ domain protein isoform X1

    See identical proteins and their annotated locations for XP_006716949.1

    UniProtKB/Swiss-Prot
    O75970, Q8N790
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2; L27_2
    pfam16667
    Location:15621626
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  8. XM_047424042.1XP_047279998.1  multiple PDZ domain protein isoform X8

  9. XM_017015253.2XP_016870742.1  multiple PDZ domain protein isoform X7

    UniProtKB/Swiss-Prot
    O75970
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:15291593
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  10. XM_047424025.1XP_047279981.1  multiple PDZ domain protein isoform X4

  11. XM_024447708.2XP_024303476.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2; L27_2
    pfam16667
    Location:15621626
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  12. XM_047424039.1XP_047279995.1  multiple PDZ domain protein isoform X8

  13. XM_047424028.1XP_047279984.1  multiple PDZ domain protein isoform X4

  14. XM_047424013.1XP_047279969.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  15. XM_047424045.1XP_047280001.1  multiple PDZ domain protein isoform X8

  16. XM_047424015.1XP_047279971.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  17. XM_047424043.1XP_047279999.1  multiple PDZ domain protein isoform X8

  18. XM_047424031.1XP_047279987.1  multiple PDZ domain protein isoform X4

  19. XM_047424046.1XP_047280002.1  multiple PDZ domain protein isoform X9

    Conserved Domains (4) summary
    smart00228
    Location:374463
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:11491240
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam09045
    Location:663
    L27_2
    pfam16667
    Location:15951659
    MPDZ_u10; Unstructured region 10 on multiple PDZ protein
  20. XM_047424037.1XP_047279993.1  multiple PDZ domain protein isoform X8

  21. XM_047424034.1XP_047279990.1  multiple PDZ domain protein isoform X6

  22. XM_047424023.1XP_047279979.1  multiple PDZ domain protein isoform X4

  23. XM_047424009.1XP_047279965.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  24. XM_047424022.1XP_047279978.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  25. XM_047424012.1XP_047279968.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  26. XM_047424036.1XP_047279992.1  multiple PDZ domain protein isoform X8

  27. XM_047424024.1XP_047279980.1  multiple PDZ domain protein isoform X4

  28. XM_047424010.1XP_047279966.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  29. XM_047424026.1XP_047279982.1  multiple PDZ domain protein isoform X4

  30. XM_047424014.1XP_047279970.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  31. XM_047424020.1XP_047279976.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  32. XM_047424019.1XP_047279975.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  33. XM_047424018.1XP_047279974.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  34. XM_047424038.1XP_047279994.1  multiple PDZ domain protein isoform X8

  35. XM_047424029.1XP_047279985.1  multiple PDZ domain protein isoform X4

  36. XM_047424017.1XP_047279973.1  multiple PDZ domain protein isoform X1

    UniProtKB/Swiss-Prot
    Q8N790
  37. XM_047424027.1XP_047279983.1  multiple PDZ domain protein isoform X4

  38. XM_047424041.1XP_047279997.1  multiple PDZ domain protein isoform X8

  39. XM_047424032.1XP_047279988.1  multiple PDZ domain protein isoform X4

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    13115022..13289090 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)