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efa1B elongation factor 1 beta [ Dictyostelium discoideum AX4 ]

Gene ID: 8624405, updated on 23-Nov-2023

Summary

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Gene symbol
efa1B
Gene description
elongation factor 1 beta
Primary source
dictyBase:DDB_G0284035
Locus tag
DDB_G0284035
Gene type
protein coding
RNA name
elongation factor 1b
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium
Old locus tag
DDBDRAFT_0185828; DDBDRAFT_0191174; DDB_0185828; DDB_0191174
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Genomic context

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Location:
chromosome: 4
Exon count:
2
Sequence:
Chromosome: 4; NC_007090.3 (1535647..1536451)

Chromosome 4 - NC_007090.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene RA domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007090.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Elongation factor 1beta is an actin-binding protein. Furukawa R, et al. Biochim Biophys Acta, 2001 Aug 15. PMID 11479029
  2. Cloning and sequence analysis of the cDNA encoding the elongation factor-1 beta of Dictyostelium discoideum. Chae S, et al. Biochim Biophys Acta, 1998 Mar 3. PMID 9546041
  3. Proteomic analysis of Legionella-containing phagosomes isolated from Dictyostelium. Shevchuk O, et al. Int J Med Microbiol, 2009 Nov. PMID 19482547
  4. Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake. Gotthardt D, et al. Mol Cell Proteomics, 2006 Dec. PMID 16926386
  5. The genome of the social amoeba Dictyostelium discoideum. Eichinger L, et al. Nature, 2005 May 5. PMID 15875012, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by dictyBase

Function Evidence Code Pubs
enables actin monomer binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
  
enables translation elongation factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament polymerization IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to bacterium HEP PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translational elongation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translational elongation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translational elongation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of eukaryotic translation elongation factor 1 complex IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation elongation factor 1 complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in phagocytic vesicle HDA PubMed 

General protein information

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Names
elongation factor 1 beta
elongation factor 1b

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007090.3 Reference assembly

    Range
    1535647..1536451
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_633643.1 → XP_638735.1  elongation factor 1b [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_638735.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O60954, Q54Q62, Q9GRF8
    Conserved Domains (2) summary
    cd10308
    Location:1 → 64
    GST_C_eEF1b_like; Glutathione S-transferase C-terminal-like, alpha helical domain of eukaryotic translation Elongation Factor 1 beta
    cd00292
    Location:128 → 216
    EF1B; Elongation factor 1 beta (EF1B) guanine nucleotide exchange domain. EF1B catalyzes the exchange of GDP bound to the G-protein, EF1A, for GTP, an important step in the elongation cycle of the protein biosynthesis. EF1A binds to and delivers the aminoacyl ...
Nucleotide Protein
Heading Accession and Version

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