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arcB actin related protein 2/3 complex, 34 kDa subunit [ Dictyostelium discoideum AX4 ]

Gene ID: 8623789, updated on 23-Nov-2023

Summary

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Gene symbol
arcB
Gene description
actin related protein 2/3 complex, 34 kDa subunit
Primary source
dictyBase:DDB_G0282813
Locus tag
DDB_G0282813
Gene type
protein coding
RNA name
actin related protein 2/3 complex, subunit 2
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium
Old locus tag
DDBDRAFT_0204976; DDBDRAFT_0214935; DDB_0204976; DDB_0214935
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Genomic context

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Location:
chromosome: 3
Exon count:
3
Sequence:
Chromosome: 3; NC_007089.4 (6271490..6272740)

Chromosome 3 - NC_007089.4Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene pterin-4-alpha-carbinolamine dehydratase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007089.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in Dictyostelium. Choi CH, et al. J Biol Chem, 2013 Jan 25. PMID 23223240, Free PMC Article
  2. Mutants in the Dictyostelium Arp2/3 complex and chemoattractant-induced actin polymerization. Langridge PD, et al. Exp Cell Res, 2007 Jul 15. PMID 17553489
  3. Vectors for expression of proteins with single or combinatorial fluorescent protein and tandem affinity purification tags in Dictyostelium. Meima ME, et al. Protein Expr Purif, 2007 Jun. PMID 17296313, Free PMC Article
  4. Subsecond reorganization of the actin network in cell motility and chemotaxis. Diez S, et al. Proc Natl Acad Sci U S A, 2005 May 24. PMID 15894626, Free PMC Article
  5. Functional analysis of Dictyostelium IBARa reveals a conserved role of the I-BAR domain in endocytosis. Veltman DM, et al. Biochem J, 2011 May 15. PMID 21401524

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in Dictyostelium
    Title: Phosphorylation of actin-related protein 2 (Arp2) is required for normal development and cAMP chemotaxis in Dictyostelium.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by dictyBase

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables actin filament binding TAS
Traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in Arp2/3 complex-mediated actin nucleation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Arp2/3 complex-mediated actin nucleation IEA
Inferred from Electronic Annotation
more info
  
involved_in actin filament depolymerization TAS
Traceable Author Statement
more info
 PubMed 
involved_in actin filament polymerization IEA
Inferred from Electronic Annotation
more info
  
involved_in actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in actin filament polymerization TAS
Traceable Author Statement
more info
 PubMed 
involved_in actin nucleation TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within exocytosis IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within phagocytosis IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
part_of Arp2/3 protein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Arp2/3 protein complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of Arp2/3 protein complex IEA
Inferred from Electronic Annotation
more info
  
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
  
colocalizes_with cell leading edge IC
Inferred by Curator
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
colocalizes_with clathrin-coated pit IDA
Inferred from Direct Assay
more info
 PubMed 
colocalizes_with cortical actin cytoskeleton IC
Inferred by Curator
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
colocalizes_with filopodium IC
Inferred by Curator
more info
 PubMed 
colocalizes_with phagocytic vesicle TAS
Traceable Author Statement
more info
 PubMed 
colocalizes_with phagocytic vesicle membrane IDA
Inferred from Direct Assay
more info
 PubMed 
colocalizes_with pseudopodium IC
Inferred by Curator
more info
 PubMed 
located_in pseudopodium IEA
Inferred from Electronic Annotation
more info
  
colocalizes_with vesicle IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Names
actin related protein 2/3 complex, 34 kDa subunit
actin related protein 2/3 complex, subunit 2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007089.4 Reference assembly

    Range
    6271490..6272740
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_634256.1 → XP_639348.1  actin related protein 2/3 complex, subunit 2 [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_639348.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O96623, Q54RY9
    Conserved Domains (1) summary
    pfam04045
    Location:50 → 277
    P34-Arc; Arp2/3 complex, 34 kD subunit p34-Arc
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q54RY9.1

Gene LinkOut

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