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DDB_G0279137 methylenetetrahydrofolate reductase [ Dictyostelium discoideum AX4 ]

Gene ID: 8621890, updated on 11-Apr-2024

Summary

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Gene symbol
DDB_G0279137
Gene description
methylenetetrahydrofolate reductase
Primary source
dictyBase:DDB_G0279137
Locus tag
DDB_G0279137
Gene type
protein coding
RNA name
methylenetetrahydrofolate reductase
RefSeq status
PROVISIONAL
Organism
Dictyostelium discoideum AX4 (strain: AX4)
Lineage
Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium
Old locus tag
DDBDRAFT_0204686; DDBDRAFT_0230137; DDB_0204686; DDB_0230137
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Genomic context

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Location:
chromosome: 3
Exon count:
1
Sequence:
Chromosome: 3; NC_007089.4 (1675769..1677652, complement)

Chromosome 3 - NC_007089.4Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene adaptor-related protein complex 1, beta 1 subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_007089.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The genome of the social amoeba Dictyostelium discoideum. Eichinger L, et al. Nature, 2005 May 5. PMID 15875012, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by dictyBase

Function Evidence Code Pubs
enables FAD binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methylenetetrahydrofolate reductase (NAD(P)H) activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methylenetetrahydrofolate reductase (NAD(P)H) activity IEA
Inferred from Electronic Annotation
more info
  
enables methylenetetrahydrofolate reductase (NAD(P)H) activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in methionine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in methionine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in tetrahydrofolate interconversion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Names
methylenetetrahydrofolate reductase

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_007089.4 Reference assembly

    Range
    1675769..1677652 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_636752.1 → XP_641844.1  methylenetetrahydrofolate reductase [Dictyostelium discoideum AX4]

    See identical proteins and their annotated locations for XP_641844.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q54X84
    Conserved Domains (1) summary
    cl00246
    Location:21 → 588
    MTHFR; Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q54X84.1

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