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RDH16 retinol dehydrogenase 16 (all-trans) [ Homo sapiens (human) ]

Gene ID: 8608, updated on 6-Dec-2016
Official Symbol
RDH16provided by HGNC
Official Full Name
retinol dehydrogenase 16 (all-trans)provided by HGNC
Primary source
HGNC:HGNC:29674
See related
Ensembl:ENSG00000139547 Vega:OTTHUMG00000170895
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RODH-4; SDR9C8
Orthologs
Location:
12q13.3
Exon count:
4
Annotation release Status Assembly Chr Location
108 current GRCh38.p7 (GCF_000001405.33) 12 NC_000012.12 (56951431..56959374, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (57345215..57353158, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene short chain dehydrogenase/reductase family 9C member 7 Neighboring gene retinol dehydrogenase 16 (all-trans) pseudogene Neighboring gene retinol dehydrogenase 16 (all-trans) pseudogene Neighboring gene G protein-coupled receptor 182 Neighboring gene HBcAg-binding protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
electron carrier activity TAS
Traceable Author Statement
more info
PubMed 
retinol dehydrogenase activity TAS
Traceable Author Statement
more info
 
Process Evidence Code Pubs
lipid metabolic process TAS
Traceable Author Statement
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle TAS
Traceable Author Statement
more info
PubMed 
organelle membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
retinol dehydrogenase 16
Names
microsomal NAD+-dependent retinol dehydrogenase 4
retinol dehydrogenase 16 (all-trans and 13-cis)
short chain dehydrogenase/reductase family 9C, member 8
sterol/retinol dehydrogenase

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320108.1NP_001307037.1  retinol dehydrogenase 16 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon and initiates translation at an alternate downstream start codon compared to variant 1. The encoded isoform (2) has a shorter, distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AB209332, AW449664
    UniProtKB/TrEMBL
    Q59FX7
    Conserved Domains (1) summary
    cl21454
    Location:46160
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
  2. NM_003708.4NP_003699.3  retinol dehydrogenase 16 isoform 1

    See identical proteins and their annotated locations for NP_003699.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AB209332, AC026120, AF057034, AW449664
    Consensus CDS
    CCDS41797.1
    UniProtKB/Swiss-Prot
    O75452
    UniProtKB/TrEMBL
    Q59FX7
    Related
    ENSP00000381206, OTTHUMP00000244666, ENST00000398138, OTTHUMT00000410898
    Conserved Domains (2) summary
    pfam00106
    Location:30218
    adh_short; short chain dehydrogenase
    cl21454
    Location:30305
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p7 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p7 Primary Assembly

    Range
    56951431..56959374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018923.2 Alternate CHM1_1.1

    Range
    57312965..57320908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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