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BMH1 14-3-3 family protein BMH1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856924, updated on 5-Jun-2017
Gene symbol
BMH1
Gene description
14-3-3 family protein BMH1
Primary source
SGD:S000000979
Locus tag
YER177W
Gene type
protein coding
RNA name
14-3-3 family protein BMH1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
APR6
See BMH1 in Map Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (545611..546414)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene Ecm32p Neighboring gene pyruvate dehydrogenase (acetyl-transferring) subunit E1 alpha Neighboring gene recombinase DMC1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA replication origin binding IDA
Inferred from Direct Assay
more info
PubMed 
RNA polymerase II activating transcription factor binding IDA
Inferred from Direct Assay
more info
PubMed 
phosphoserine residue binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein domain specific binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA damage checkpoint IMP
Inferred from Mutant Phenotype
more info
PubMed 
Ras protein signal transduction IGI
Inferred from Genetic Interaction
more info
PubMed 
aggresome assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
ascospore formation IGI
Inferred from Genetic Interaction
more info
PubMed 
fungal-type cell wall chitin biosynthetic process IGI
Inferred from Genetic Interaction
more info
PubMed 
glycogen metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
mitotic spindle orientation checkpoint IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle IPI
Inferred from Physical Interaction
more info
PubMed 
pseudohyphal growth IGI
Inferred from Genetic Interaction
more info
PubMed 
signal transduction involved in filamentous growth IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
Names
14-3-3 family protein BMH1
NP_011104.3
  • 14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of exocytosis, vesicle transport, Ras/MAPK and rapamycin-sensitive signaling, aggresome formation, spindle position checkpoint; protein increases in abundance and relative distribution to the nucleus increases upon DNA replication stress; antiapoptotic gene similar to human 14-3-3; BMH1 has a paralog, BMH2, that arose from whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    545611..546414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179067.3NP_011104.3  TPA: 14-3-3 family protein BMH1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011104.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P29311
    Conserved Domains (1) summary
    COG5040
    Location:1267
    BMH1; 14-3-3 family protein [Signal transduction mechanisms]
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