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RPH1 Rph1p [ Saccharomyces cerevisiae S288c ]

Gene ID: 856916, updated on 17-Sep-2016
Gene symbol
RPH1
Gene description
Rph1p
Primary source
SGD:S000000971
Locus tag
YER169W
Gene type
protein coding
RNA name
Rph1p
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
KDM4
See RPH1 in Map Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (523369..525759)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Bck2p Neighboring gene tRNA adenylyltransferase Neighboring gene adenylate kinase ADK2 Neighboring gene TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Component Evidence Code Pubs
nucleus IC
Inferred by Curator
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Rph1p
NP_011096.1
  • JmjC domain-containing histone demethylase; targets tri- and dimethylated H3K36; associates with actively transcribed regions and promotes elongation; repressor of autophagy-related genes in nutrient-replete conditions; damage-responsive repressor of PHR1; phosphorylated by the Rad53p-dependent DNA damage checkpoint pathway and by a Rim1p-mediated event during starvation; target of stress-induced hormesis; RPH1 has a paralog, GIS1, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    523369..525759
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179059.1NP_011096.1  Rph1p [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_011096.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P39956
    Conserved Domains (6) summary
    smart00545
    Location:1354
    JmjN; Small domain found in the jumonji family of transcription factors
    pfam02373
    Location:222338
    JmjC; JmjC domain, hydroxylase
    COG5048
    Location:507759
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:711732
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:723749
    zf-H2C2_2; Zinc-finger double domain
    pfam13894
    Location:709732
    zf-C2H2_4; C2H2-type zinc finger
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