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SWI4 SBF complex DNA-binding subunit SWI4 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856847, updated on 5-Jun-2017
Gene symbol
SWI4
Gene description
SBF complex DNA-binding subunit SWI4
Primary source
SGD:S000000913
Locus tag
YER111C
Gene type
protein coding
RNA name
SBF complex DNA-binding subunit SWI4
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ART1
See SWI4 in Map Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (382595..385876, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Kap123p Neighboring gene U6 snRNA complex subunit LSM4 Neighboring gene Tmn3p

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Cell Cycle and Cell Division, organism-specific biosystem (from WikiPathways)
    Cell Cycle and Cell Division, organism-specific biosystem(From http://en.wikipedia.org/wiki/Cell_cycle) The cell cycle is the series of events that takes place in a cell leading to its division and duplication (replication). Regulation of the cell cycle in...
  • Cell cycle - yeast, organism-specific biosystem (from KEGG)
    Cell cycle - yeast, organism-specific biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps (G1 and G2 phases). G1, S, and G...
  • Cell cycle - yeast, conserved biosystem (from KEGG)
    Cell cycle - yeast, conserved biosystemMitotic cell cycle progression is accomplished through a reproducible sequence of events, DNA replication (S phase) and mitosis (M phase) separated temporally by gaps (G1 and G2 phases). G1, S, and G...
  • MAPK Signaling Pathway, organism-specific biosystem (from WikiPathways)
    MAPK Signaling Pathway, organism-specific biosystemThe MAPK/ERK pathway is a signal transduction pathway that couples intracellular responses to the binding of growth factors to cell surface receptors. In many cell types, activation of this pathway p...
  • MAPK signaling pathway - yeast, organism-specific biosystem (from KEGG)
    MAPK signaling pathway - yeast, organism-specific biosystemThe S. cerevisiae genome encodes multiple MAP kinase orthologs. One (Fus3) mediates cellular response to peptide pheromones. Another (Kss1) permits adjustment to nutrient limiting conditions. A third...
  • MAPK signaling pathway - yeast, conserved biosystem (from KEGG)
    MAPK signaling pathway - yeast, conserved biosystemThe S. cerevisiae genome encodes multiple MAP kinase orthologs. One (Fus3) mediates cellular response to peptide pheromones. Another (Kss1) permits adjustment to nutrient limiting conditions. A third...
  • Meiosis - yeast, organism-specific biosystem (from KEGG)
    Meiosis - yeast, organism-specific biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, one pair of sister chromatids recombines with, th...
  • Meiosis - yeast, conserved biosystem (from KEGG)
    Meiosis - yeast, conserved biosystemDuring meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II. At meiosis I, one pair of sister chromatids recombines with, th...
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
NOT asparaginase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
MBF transcription complex IBA
Inferred from Biological aspect of Ancestor
more info
 
SBF transcription complex IDA
Inferred from Direct Assay
more info
PubMed 
SBF transcription complex IEA
Inferred from Electronic Annotation
more info
 
SBF transcription complex IMP
Inferred from Mutant Phenotype
more info
PubMed 
SBF transcription complex IPI
Inferred from Physical Interaction
more info
PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
nuclear chromatin IDA
Inferred from Direct Assay
more info
PubMed 
Names
SBF complex DNA-binding subunit SWI4
NP_011036.1
  • DNA binding component of the SBF complex (Swi4p-Swi6p); a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair; Slt2p-independent regulator of cold growth; acetylation at two sites, K1016 and K1066, regulates interaction with Swi6p

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    382595..385876 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179001.1NP_011036.1  TPA: SBF complex DNA-binding subunit SWI4 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011036.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P25302
    Conserved Domains (3) summary
    cd00204
    Location:516662
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam04383
    Location:56123
    KilA-N; KilA-N domain
    sd00045
    Location:521551
    ANK; ANK repeat [structural motif]
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