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RAD51 recombinase RAD51 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856831, updated on 5-Sep-2021

Summary

Gene symbol
RAD51
Gene description
recombinase RAD51
Primary source
SGD:S000000897
Locus tag
YER095W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MUT5
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Genomic context

See RAD51 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (349980..351182)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Aim11p Neighboring gene proteasome core particle subunit beta 3 Neighboring gene Shc1p Neighboring gene tRNA

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the RAD51 gene: The RAD51 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP-dependent activity, acting on DNA IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ATP-dependent activity, acting on DNA IDA
Inferred from Direct Assay
more info
PubMed 
enables ATP-dependent activity, acting on DNA IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA strand exchange activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA strand exchange activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA strand exchange activity IEA
Inferred from Electronic Annotation
more info
 
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables double-stranded DNA binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables single-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables single-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA recombinase assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in DNA recombination IDA
Inferred from Direct Assay
more info
PubMed 
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
involved_in chromosome organization involved in meiotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in double-strand break repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 
involved_in heteroduplex formation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in meiotic joint molecule formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitochondrial DNA repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic recombination-dependent replication fork processing IEA
Inferred from Electronic Annotation
more info
 
involved_in nucleotide-excision repair IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in reciprocal meiotic recombination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in strand invasion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in strand invasion IDA
Inferred from Direct Assay
more info
PubMed 
involved_in telomere maintenance via recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in condensed nuclear chromosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in condensed nuclear chromosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear chromosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
recombinase RAD51
NP_011021.3
  • Strand exchange protein; forms helical filament with DNA that searches for homology; involved in recombinational repair of DNS DSBs during vegetative growth and meiosis; phosphorylation by Cdc28p in G2/M phase promotes DNA binding, strand invasion, and primer extension; L1 and L2 motifs of DNA binding site I have critical roles in ensuring DNA fidelity during meiotic recombination; RAD51 and RAD4 pathways confer resistance to benzo[a]pyrene dihydrodiol; homolog of Dmc1p and bacterial RecA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    349980..351182
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178986.3NP_011021.3  TPA: recombinase RAD51 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011021.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P25454
    Conserved Domains (1) summary
    TIGR02239
    Location:83397
    recomb_RAD51; DNA repair protein RAD51
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