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ALD5 aldehyde dehydrogenase (NAD(P)(+)) ALD5 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856804, updated on 18-Jan-2023

Summary

Gene symbol
ALD5
Gene description
aldehyde dehydrogenase (NAD(P)(+)) ALD5
Primary source
SGD:S000000875
Locus tag
YER073W
See related
AllianceGenome:SGD:S000000875
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables aldehyde dehydrogenase (NAD+) activity. Involved in acetate biosynthetic process. Located in mitochondrion. Orthologous to several human genes including ALDH1A1 (aldehyde dehydrogenase 1 family member A1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See ALD5 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (304030..305592)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Tda2p Neighboring gene Vtc1p Neighboring gene ribosomal 40S subunit protein S24A Neighboring gene Yos1p

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
aldehyde dehydrogenase (NAD(P)(+)) ALD5
NP_010996.2
  • Mitochondrial aldehyde dehydrogenase; involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    304030..305592
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178964.2NP_010996.2  TPA: aldehyde dehydrogenase (NAD(P)(+)) ALD5 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010996.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZR27, D3DLX8, P40047
    UniProtKB/TrEMBL
    A0A0L8VRP0, A0A6A5PX70, B3LRJ0, C7GRQ5, C8Z781, H0GF58, N1P4W5
    Conserved Domains (1) summary
    cd07091
    Location:41513
    ALDH_F1-2_Ald2-like; ALDH subfamily: ALDH families 1and 2, including 10-formyltetrahydrofolate dehydrogenase, NAD+-dependent retinal dehydrogenase 1 and related proteins