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GPP2 glycerol-1-phosphatase HOR2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856791, updated on 10-Aug-2022

Summary

Gene symbol
GPP2
Gene description
glycerol-1-phosphatase HOR2
Primary source
SGD:S000000864
Locus tag
YER062C
See related
AllianceGenome:SGD:S000000864
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
HOR2
Summary
Enables glycerol-1-phosphatase activity. Involved in glycerol biosynthetic process and response to osmotic stress. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See GPP2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (279930..280682, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene purine-cytosine permease Neighboring gene fatty acid synthase CEM1 Neighboring gene Tho1p Neighboring gene Vhr2p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables beta-phosphoglucomutase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables glycerol-1-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables glycerol-1-phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables glycerol-1-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular carbohydrate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in glycerol biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glycerol biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to osmotic stress IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in response to osmotic stress IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
glycerol-1-phosphatase HOR2
NP_010984.3
  • DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis; also known as glycerol-1-phosphatase; induced in response to hyperosmotic or oxidative stress, and during diauxic shift; GPP2 has a paralog, GPP1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    279930..280682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178953.3NP_010984.3  TPA: glycerol-1-phosphatase HOR2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010984.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLW7, P40106
    UniProtKB/TrEMBL
    A0A0L8VRQ4, A0A6A5PWG8, A0A6C1DRF1, A0A815Y886, B5VHJ4, C7GTD0, C8Z768, N1P561
    Conserved Domains (1) summary
    cd07527
    Location:14227
    HAD_ScGPP-like; subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p)