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GIP2 Gip2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856781, updated on 18-Jan-2023

Summary

Gene symbol
GIP2
Gene description
Gip2p
Primary source
SGD:S000000856
Locus tag
YER054C
See related
AllianceGenome:SGD:S000000856
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables protein phosphatase regulator activity. Involved in glycogen metabolic process and protein dephosphorylation. Part of protein phosphatase type 1 complex. Orthologous to several human genes including PPP1R3B (protein phosphatase 1 regulatory subunit 3B); PPP1R3C (protein phosphatase 1 regulatory subunit 3C); and PPP1R3D (protein phosphatase 1 regulatory subunit 3D). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See GIP2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (262052..263698, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene Cu/Pi carrier Neighboring gene uncharacterized protein Neighboring gene ATP phosphoribosyltransferase Neighboring gene purine-cytosine permease

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables glycogen binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein phosphatase 1 binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein phosphatase regulator activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in glycogen metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of glycogen biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of protein phosphatase type 1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of protein phosphatase type 1 complex IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
Gip2p
NP_010974.1
  • Putative regulatory subunit of protein phosphatase Glc7p; involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p; GIP2 has a paralog, PIG2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    262052..263698 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178945.1NP_010974.1  TPA: Gip2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010974.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLV7, P40036
    UniProtKB/TrEMBL
    A0A8H8ULS0
    Conserved Domains (1) summary
    pfam03370
    Location:429534
    CBM_21; Carbohydrate/starch-binding module (family 21)