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CIN8 kinesin motor protein CIN8 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856648, updated on 5-Sep-2021

Summary

Gene symbol
CIN8
Gene description
kinesin motor protein CIN8
Primary source
SGD:S000000787
Locus tag
YEL061C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
KSL2; SDS15
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Genomic context

See CIN8 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (36535..39537, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene arginine permease CAN1 Neighboring gene nitrogen permease regulating protein NPR2 Neighboring gene proteinase B Neighboring gene Som1p

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 
enables microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 
enables microtubule motor activity IGI
Inferred from Genetic Interaction
more info
PubMed 
enables minus-end-directed microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables minus-end-directed microtubule motor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables minus-end-directed microtubule motor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables plus-end-directed microtubule motor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables plus-end-directed microtubule motor activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in initial mitotic spindle pole body separation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in initial mitotic spindle pole body separation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in meiotic sister chromatid segregation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in microtubule depolymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 
involved_in mitotic sister chromatid segregation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in mitotic spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitotic spindle assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in mitotic spindle elongation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of mitotic sister chromatid segregation IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in astral microtubule IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in kinetochore IDA
Inferred from Direct Assay
more info
PubMed 
located_in kinetochore microtubule IDA
Inferred from Direct Assay
more info
PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in spindle IEA
Inferred from Electronic Annotation
more info
 
is_active_in spindle microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in spindle microtubule IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
kinesin motor protein CIN8
NP_010853.2
  • Bipolar kinesin motor protein; switches from minus- to plus-end-directed motility in vitro depending on conditions; involved in mitotic spindle assembly and chromosome segregation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    36535..39537 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178876.1NP_010853.2  TPA: kinesin motor protein CIN8 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010853.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P27895
    Conserved Domains (3) summary
    COG1196
    Location:493772
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd01364
    Location:34486
    KISc_BimC_Eg5; Kinesin motor domain, BimC/Eg5 spindle pole proteins
    pfam15921
    Location:677928
    CCDC158; Coiled-coil domain-containing protein 158
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