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CAN1 arginine permease CAN1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856646, updated on 18-Jan-2023

Summary

Gene symbol
CAN1
Gene description
arginine permease CAN1
Primary source
SGD:S000000789
Locus tag
YEL063C
See related
AllianceGenome:SGD:S000000789
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables L-arginine transmembrane transporter activity. Involved in L-arginine transmembrane transport. Located in eisosome and plasma membrane. Orthologous to several human genes including SLC7A1 (solute carrier family 7 member 1); SLC7A2 (solute carrier family 7 member 2); and SLC7A3 (solute carrier family 7 member 3). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See CAN1 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (31694..33466, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene siderophore transporter Neighboring gene Avt2p Neighboring gene nitrogen permease regulating protein NPR2 Neighboring gene kinesin motor protein CIN8

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Process Evidence Code Pubs
involved_in L-arginine transmembrane transport IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
 
involved_in basic amino acid transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in nitrogen compound transport IEA
Inferred from Electronic Annotation
more info
 
involved_in organic substance transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in eisosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in endoplasmic reticulum HDA PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
arginine permease CAN1
NP_010851.1
  • Plasma membrane arginine permease; requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance; CAN1 has a paralog, ALP1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    31694..33466 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178878.1NP_010851.1  TPA: arginine permease CAN1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010851.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLI7, P04817
    UniProtKB/TrEMBL
    A0A8H8ULF2, G2WCH1
    Conserved Domains (1) summary
    TIGR00913
    Location:85562
    2A0310; amino acid permease (yeast)