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RPN10 proteasome regulatory particle base subunit RPN10 [ Saccharomyces cerevisiae S288c ]

Gene ID: 856607, updated on 5-Mar-2017
Gene symbol
RPN10
Gene description
proteasome regulatory particle base subunit RPN10
Primary source
SGD:S000001243
Locus tag
YHR200W
Gene type
protein coding
RNA name
proteasome regulatory particle base subunit RPN10
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288c (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MCB1; SUN1
See RPN10 in Map Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (499079..499885)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Aim46p Neighboring gene Nbl1p Neighboring gene exopolyphosphatase Neighboring gene hypothetical protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
polyubiquitin binding IDA
Inferred from Direct Assay
more info
PubMed 
structural molecule activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
proteasome assembly IBA
Inferred from Biological aspect of Ancestor
more info
 
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-dependent protein catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
proteasome complex IEA
Inferred from Electronic Annotation
more info
 
proteasome complex IMP
Inferred from Mutant Phenotype
more info
PubMed 
proteasome regulatory particle, base subcomplex IDA
Inferred from Direct Assay
more info
PubMed 
proteasome regulatory particle, base subcomplex IEA
Inferred from Electronic Annotation
more info
 
proteasome regulatory particle, base subcomplex IPI
Inferred from Physical Interaction
more info
PubMed 
Names
proteasome regulatory particle base subunit RPN10
NP_012070.3
  • Non-ATPase base subunit of the 19S RP of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the regulatory particle (RP); binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    499079..499885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179331.3NP_012070.3  TPA: proteasome regulatory particle base subunit RPN10 [Saccharomyces cerevisiae S288c]

    See identical proteins and their annotated locations for NP_012070.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38886
    Conserved Domains (1) summary
    COG5148
    Location:1236
    RPN10; 26S proteasome regulatory complex, subunit RPN10/PSMD4 [Posttranslational modification, protein turnover, chaperones]
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