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IKI1 Elongator subunit IKI1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856594, updated on 5-Nov-2017
Gene symbol
IKI1
Gene description
Elongator subunit IKI1
Primary source
SGD:S000001230
Locus tag
YHR187W
Gene type
protein coding
RNA name
Elongator subunit IKI1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288c)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ELP5; HAP2; TOT5
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (480990..481919)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene tRNA Neighboring gene ubiquitin-binding TORC1 subunit KOG1 Neighboring gene GPI-anchor transamidase subunit GPI16 Neighboring gene aminoacyl-tRNA hydrolase

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
contributes_to ATPase activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to ATPase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
contributes_to tRNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
tRNA modification IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Elongator holoenzyme complex IDA
Inferred from Direct Assay
more info
PubMed 
Elongator holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Names
Elongator subunit IKI1
NP_012057.3
  • Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex; which is required for modification of wobble nucleosides in tRNA; iki1 mutations confer resistance to the K. lactis toxin zymocin

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    480990..481919
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179318.3NP_012057.3  TPA: Elongator subunit IKI1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012057.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38874
    Conserved Domains (1) summary
    pfam10483
    Location:11290
    Elong_Iki1; Elongator subunit Iki1
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