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ENO2 phosphopyruvate hydratase ENO2 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856579, updated on 5-Sep-2021

Summary

Gene symbol
ENO2
Gene description
phosphopyruvate hydratase ENO2
Primary source
SGD:S000001217
Locus tag
YHR174W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
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Genomic context

See ENO2 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (451327..452640)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Spc97p Neighboring gene uncharacterized protein Neighboring gene low-affinity Cu transporter Neighboring gene uncharacterized protein

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

  • Homologs of the ENO2 gene: The ENO2 gene is conserved in human, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, and N.crassa.

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables melatonin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphopyruvate hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphopyruvate hydratase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphopyruvate hydratase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in glycolytic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 
involved_in glycolytic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of vacuole fusion, non-autophagic IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of vacuole fusion, non-autophagic IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
phosphopyruvate hydratase ENO2
NP_012044.1
  • Enolase II, a phosphopyruvate hydratase; catalyzes conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression induced in response to glucose; ENO2 has a paralog, ENO1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    451327..452640
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179305.1NP_012044.1  TPA: phosphopyruvate hydratase ENO2 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012044.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P00925
    Conserved Domains (1) summary
    PTZ00081
    Location:1430
    PTZ00081; enolase; Provisional
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