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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 856543, updated on 3-May-2025
Official Full Name
uncharacterized protein
Primary source
SGD:S000001182
Locus tag
YHR140W
See related
AllianceGenome:SGD:S000001182; FungiDB:YHR140W; VEuPathDB:YHR140W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in endoplasmic reticulum. Orthologous to human ADTRP (androgen dependent TFPI regulating protein) and AIG1 (androgen induced 1). [provided by Alliance of Genome Resources, May 2025]
Orthologs
all
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Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (380572..381291)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Sps100p Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ribosomal 60S subunit protein L42B

Genomic Sequence:
NC_001140.6

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Predicting subcellular localization of proteins using protein-protein interaction data. Garapati HS, et al. Genomics, 2020 May. PMID 31945465
  2. Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions. Kim H, et al. J Biol Chem, 2003 Mar 21. PMID 12524434
  3. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII. Johnston M, et al. Science, 1994 Sep 30. PMID 8091229
  4. Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability. Mishra PK, et al. Mol Biol Cell, 2023 Sep 1. PMID 37436802, Free PMC Article
  5. Large-scale identification of yeast integral membrane protein interactions. Miller JP, et al. Proc Natl Acad Sci U S A, 2005 Aug 23. PMID 16093310, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum HDA PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
uncharacterized protein
NP_012009.1
  • Endoplasmic reticulum protein; may contribute to maintenance of ER and nuclear morphology; null mutant shows discontinuity in nuclear envelope, clustering of nuclear pores, and lacks cortical ER

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    380572..381291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179270.1 → NP_012009.1  TPA: uncharacterized protein YHR140W [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012009.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DL89, P38842, Q6B2K3
    UniProtKB/TrEMBL
    A6ZT48, B3LSQ4, C7GTW7, C8Z9T7, G2WFL3, N1P2C1
    Conserved Domains (1) summary
    pfam04750
    Location:83 → 220
    Far-17a_AIG1; FAR-17a/AIG1-like protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38842.2

Gene LinkOut

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