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DMA1 ubiquitin-conjugating protein DMA1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856515, updated on 8-Apr-2018
Gene symbol
DMA1
Gene description
ubiquitin-conjugating protein DMA1
Primary source
SGD:S000001157
Locus tag
YHR115C
Gene type
protein coding
RNA name
ubiquitin-conjugating protein DMA1
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
CHF1
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (340109..341359, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene aspartyl aminopeptidase Neighboring gene Bzz1p Neighboring gene Cox23p Neighboring gene protein channel TOM71

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-protein transferase activity IDA
Inferred from Direct Assay
more info
PubMed 
ubiquitin-protein transferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cell division IEA
Inferred from Electronic Annotation
more info
 
cellular bud neck septin ring organization IGI
Inferred from Genetic Interaction
more info
PubMed 
establishment of mitotic spindle orientation IGI
Inferred from Genetic Interaction
more info
PubMed 
mitotic spindle orientation checkpoint IGI
Inferred from Genetic Interaction
more info
PubMed 
protein autoubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
protein localization to bud neck IGI
Inferred from Genetic Interaction
more info
PubMed 
protein ubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
regulation of formin-nucleated actin cable assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of formin-nucleated actin cable assembly IPI
Inferred from Physical Interaction
more info
PubMed 
septin ring assembly IGI
Inferred from Genetic Interaction
more info
PubMed 
ubiquitin-dependent protein catabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm HDA PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
ubiquitin-conjugating protein DMA1
NP_011983.1
  • Ubiquitin-protein ligase (E3); controls septin dynamics, spindle position checkpoint (SPOC) with ligase Dma2p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p; ortholog of human RNF8, similar to human Chfr; contains FHA, RING fingers; DMA1 has a paralog, DMA2, that arose from the whole genome duplication

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    340109..341359 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179245.1NP_011983.1  TPA: ubiquitin-conjugating protein DMA1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011983.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38823
    Conserved Domains (2) summary
    COG1716
    Location:121308
    FHA; Forkhead associated (FHA) domain, binds pSer, pThr, pTyr [Signal transduction mechanisms]
    cd16458
    Location:325371
    RING-H2_Dmap_like; RING finger, H2 subclass, found in defective in mitotic arrest proteins (Dmap) and similar proteins
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