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YHK8 Yhk8p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856444, updated on 7-Jun-2026
Official Symbol
YHK8
Official Full Name
Yhk8p
Primary source
SGD:S000001090
Locus tag
YHR048W
See related
AllianceGenome:SGD:S000001090; FungiDB:YHR048W; VEuPathDB:YHR048W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in xenobiotic detoxification by transmembrane export across the plasma membrane. Predicted to act upstream of or within proton transmembrane transport. Located in cell periphery. [provided by Alliance of Genome Resources, Apr 2025]
Orthologs
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Try the new Transcripts and proteins table
See YHK8 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (204607..206151)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene inositol monophosphate 1-phosphatase INM1 Neighboring gene arginine/alanine aminopeptidase Neighboring gene putative serine hydrolase Neighboring gene divalent metal ion transporter SMF2

Genomic Sequence:
NC_001140.6
Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in export across plasma membrane IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in xenobiotic detoxification by transmembrane export across the plasma membrane ISA
Inferred from Sequence Alignment
more info
PubMed 
involved_in xenobiotic transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Preferred Names
Yhk8p
NP_011914.1
  • Presumed antiporter of the major facilitator superfamily; member of the 12-spanner drug:H(+) antiporter DHA1 family; expression of gene is up-regulated in cells exhibiting reduced susceptibility to azoles

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    204607..206151
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179178.1NP_011914.1  Yhk8p

    See identical proteins and their annotated locations for NP_011914.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DKZ6, P38776
    UniProtKB/TrEMBL
    A6ZSV5, B5VJX9, C7GT87, C8ZAB9, N1P9M5
    Conserved Domains (1) summary
    cd17323
    Location:77505
    MFS_Tpo1_MDR_like; Yeast Polyamine transporter 1 (Tpo1) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily