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RRM3 DNA helicase [ Saccharomyces cerevisiae S288C ]

Gene ID: 856426, updated on 31-Aug-2021

Summary

Gene symbol
RRM3
Gene description
DNA helicase
Primary source
SGD:S000001073
Locus tag
YHR031C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RTT104
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Genomic context

See RRM3 in Genome Data Viewer
Location:
chromosome: VIII
Exon count:
1
Sequence:
Chromosome: VIII; NC_001140.6 (170799..172970, complement)

Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene Yhi9p Neighboring gene mitogen-activated serine/threonine-protein kinase SLT2 Neighboring gene Erc1p Neighboring gene putative glutamate 5-kinase

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables 5'-3' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA helicase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables G-quadruplex DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables helicase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in DNA duplex unwinding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 
involved_in DNA replication IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in G-quadruplex DNA unwinding IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial genome maintenance IEA
Inferred from Electronic Annotation
more info
 
involved_in mitochondrial genome maintenance IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in ncRNA transcription IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in replication fork progression beyond termination site IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in replication fork reversal IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in telomere maintenance IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear replication fork IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
is_active_in replication fork IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in replication fork IDA
Inferred from Direct Assay
more info
PubMed 
located_in replication fork IEA
Inferred from Electronic Annotation
more info
 
located_in replication fork IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
DNA helicase
NP_011896.1
  • DNA helicase involved in rDNA replication and Ty1 transposition; binds to and suppresses DNA damage at G4 motifs in vivo; relieves replication fork pauses at telomeric regions; structurally and functionally related to Pif1p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001140.6 Reference assembly

    Range
    170799..172970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179161.1NP_011896.1  TPA: DNA helicase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_011896.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P38766
    Conserved Domains (2) summary
    COG0507
    Location:37723
    RecD; ATP-dependent exoDNAse (exonuclease V), alpha subunit, helicase superfamily I [Replication, recombination and repair]
    cd18037
    Location:235414
    DEXSc_Pif1_like; DEAD-box helicase domain of Pif1
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